Hyperbaric oxygen therapy for sudden sensorineural hearing loss (Review)
- Authors:
- Yuting Sun
- Shangyuan Wang
- Huimin Fu
- Xiaoli Ge
- Shuming Pan
-
Affiliations: Emergency Department, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, P.R. China, Emergency Department, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 202150, P.R. China, Emergency Department, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China - Published online on: September 2, 2025 https://doi.org/10.3892/mmr.2025.13672
- Article Number: 307
-
Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
 |
|
Ying YM, Tseng CC, Shin J and Rauch S: Natural history of untreated idiopathic sudden sensorineural hearing loss. Laryngoscope. 134 (Suppl 9):S1–S15. 2024. View Article : Google Scholar : PubMed/NCBI | |
|
Xie S, Qiang Q, Mei L, He C, Feng Y, Sun H and Wu X: Multivariate analysis of prognostic factors for idiopathic sudden sensorineural hearing loss treated with adjuvant hyperbaric oxygen therapy. Eur Arch Otorhinolaryngol. 275:47–51. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Feng T, Zhang Q, Wei J, Wang X and Geng Y: Effects of alprostadil combined with hyperbaric oxygen on hearing recovery and hemorheology in patients with sudden sensorineural hearing loss and analysis of related influencing factors. Exp Ther Med. 23:2422022. View Article : Google Scholar : PubMed/NCBI | |
|
Çiçek T, Özbilen Acar G and Özdamar Oİ: Evaluation of neutrophil/lymphocyte and platelet/lymphocyte ratios in sudden sensorineural hearing loss and relationship with hyperbaric oxygen therapy. J Int Adv Otol. 17:96–102. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Li H, Zhao D, Diao M, Yang C, Zhang Y, Lv Y, Zhao J and Pan S: Hyperbaric oxygen treatments attenuate the neutrophil-to-lymphocyte ratio in patients with idiopathic sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 153:606–612. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, et al: Clinical practice guideline: Sudden hearing loss (update). Otolaryngol Head Neck Surg. 161 (1_suppl):S1–S45. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Frosolini A, Franz L, Daloiso A, Lovato A, de Filippis C and Marioni G: Digging into the role of inflammatory biomarkers in sudden sensorineural hearing loss diagnosis and prognosis: A systematic review and meta-analysis. Medicina (Kaunas). 58:9632022. View Article : Google Scholar : PubMed/NCBI | |
|
Tsuzuki N and Wasano K: Idiopathic sudden sensorineural hearing loss: A review focused on the contribution of vascular pathologies. Auris Nasus Larynx. 51:747–754. 2024. View Article : Google Scholar : PubMed/NCBI | |
|
Mei X, Atturo F, Wadin K, Larsson S, Agrawal S, Ladak HM, Li H and Rask-Andersen H: Human inner ear blood supply revisited: The uppsala collection of temporal bone-an international resource of education and collaboration. Ups J Med Sci. 123:131–142. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Xie W, Dai Q, Liu J, Liu Y, Hellström S and Duan M: Analysis of clinical and laboratory findings of idiopathic sudden sensorineural hearing loss. Sci Rep. 10:60572020. View Article : Google Scholar : PubMed/NCBI | |
|
Wang S, Ye Q and Pan Y: Serum non-high-density lipoprotein cholesterol is associated with the risk of sudden sensorineural hearing loss. Medicine (Baltimore). 99:e191752020. View Article : Google Scholar : PubMed/NCBI | |
|
Fasano T, Pilia A, Vecchia L, Pertinhez TA, Lasagni D, Baricchi R, Tribi L and Bianchin G: In response to laboratory assessment of sudden sensorineural hearing loss: A case-control study. Laryngoscope. 127:E4212017. View Article : Google Scholar : PubMed/NCBI | |
|
Ulu Ş, Kınar A, Bucak A and Özdemir M: Systemic immune inflammatory index of patients with idiopathic sudden sensorineural hearing loss: Comparison of NLR and PRL values. Ear Nose Throat J. 100:726–730. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Qiao XF, Li X, Wang GP, Bai YH, Zheng W and Li TL: Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with sudden sensorineural hearing loss. Med Princ Pract. 28:23–27. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Pawlak-Osinska K, Golda R, Osinski S, Kazmierczak H, Krumrych W, Marzec M and Przybylski G: Circulating immune complexes and heat shock protein 70 in the sera of patients with sudden sensorineural hearing loss. J Int Adv Otol. 14:426–431. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Y, Jia X, Liu X, Zhao L, Zhou Y, Liang F, Gao Y and Yang J: Hyperbaric oxygen therapy promotes hearing gain with increases in serum IGF-1 and HSP70 in patients with idiopathic sudden sensorineural hearing loss. Evid Based Complement Alternat Med. 2022:13687832022. View Article : Google Scholar : PubMed/NCBI | |
|
Baradaranfar M, Dadgarnia M, Zand V, Vaziribozorg S, Mirzade FS and Mirzade M: The role of immunological factors on sudden sensoryneural hearing loss. Iran J Otorhinolaryngol. 30:219–223. 2018.PubMed/NCBI | |
|
Plontke SK, Meisner C, Agrawal S, Cayé-Thomasen P, Galbraith K, Mikulec AA, Parnes L, Premakumar Y, Reiber J, Schilder AG and Liebau A: Intratympanic corticosteroids for sudden sensorineural hearing loss. Cochrane Database Syst Rev. 7:CD0080802022.PubMed/NCBI | |
|
Kilic O, Kalcioglu MT, Cag Y, Tuysuz O, Pektas E, Caskurlu H and Cetın F: Could sudden sensorineural hearing loss be the sole manifestation of covid-19? An investigation into SARS-cov-2 in the etiology of sudden sensorineural hearing loss. Int J Infect Dis. 97:208–211. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhuang W, Wang C, Shi X, Qiu S, Zhang S, Xu B, Chen M, Jiang W, Dong H and Qiao Y: MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss. Int J Mol Med. 41:3448–3456. 2018.PubMed/NCBI | |
|
Ortega MA, Fraile-Martinez O, García-Montero C, Callejón-Peláez E, Sáez MA, Álvarez-Mon MA, García-Honduvilla N, Monserrat J, Álvarez-Mon M, Bujan J and Canals ML: A general overview on the hyperbaric oxygen therapy: Applications, mechanisms and translational opportunities. Medicina (Kaunas). 57:8642021. View Article : Google Scholar : PubMed/NCBI | |
|
Almutairi N, Alnofal E, Algouhi A, Bamajboor AS and Alzaher N: The effectiveness of hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: A retrospective study. Cureus. 12:e108192020.PubMed/NCBI | |
|
Bayoumy AB and de Ru JA: The use of hyperbaric oxygen therapy in acute hearing loss: A narrative review. Eur Arch Otorhinolaryngol. 276:1859–1880. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Olex-Zarychta D: Hyperbaric oxygenation as adjunctive therapy in the treatment of sudden sensorineural hearing loss. Int J Mol Sci. 21:85882020. View Article : Google Scholar : PubMed/NCBI | |
|
Dünnwald T, Held J, Balan P, Pecher O, Zeiger T, Hartig F, Mur E, Weiss G and Schobersberger W: Combined hyperbaric oxygen partial pressure at 1.4 bar with infrared radiation: A useful tool to improve tissue hypoxemia? Med Sci Monit. 24:4009–4019. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Yamamoto N, Takada R, Maeda T, Yoshii T, Okawa A and Yagishita K: Microcirculation and tissue oxygenation in the head and limbs during hyperbaric oxygen treatment. Diving Hyperb Med. 51:338–344. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Tian G, Zhang S and Yang J: Coexistence of IL-6 −572C/G and ICAM-1 K469E polymorphisms among patients with sudden sensorineural hearing loss. Tohoku J Exp Med. 245:7–12. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Yoon SH, Kim ME, Kim HY, Lee JS and Jang CH: Inflammatory cytokines and mononuclear cells in sudden sensorineural hearing loss. J Laryngol Otol. 133:95–101. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liu XH, Liang F, Jia XY, Zhao L, Zhou Y and Yang J: Hyperbaric oxygen treatment improves hearing level via attenuating TLR4/NF-κB mediated inflammation in sudden sensorineural hearing loss patients. Biomed Environ Sci. 33:331–337. 2020.PubMed/NCBI | |
|
Zhao T, Zhu Y, Yao L, Liu L and Li N: IGF-1 alleviates CCl4-induced hepatic cirrhosis and dysfunction of intestinal barrier through inhibition TLR4/NF-κB signaling mediated by down-regulation HMGB1. Ann Hepatol. 26:1005602021. View Article : Google Scholar : PubMed/NCBI | |
|
Rogers SC, Ge X, Brummet M, Lin X, Timm DD, D'Avignon A, Garbow JR, Kao J, Prakash J, Issaian A, et al: Quantifying dynamic range in red blood cell energetics: Evidence of progressive energy failure during storage. Transfusion. 61:1586–1599. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Bai X, Chen S, Xu K, Jin Y, Niu X, Xie L, Qiu Y, Liu XZ and Sun Y: N-acetylcysteine combined with dexamethasone treatment improves sudden sensorineural hearing loss and attenuates hair cell death caused by ros stress. Front Cell Dev Biol. 9:6594862021. View Article : Google Scholar : PubMed/NCBI | |
|
Wang S, Hou K, Gui S, Ma Y, Wang S, Zhao S and Zhu X: Insulin-like growth factor 1 in heat stress-induced neuroinflammation: Novel perspective about the neuroprotective role of chromium. Stress Biol. 3:232023. View Article : Google Scholar : PubMed/NCBI | |
|
Choi Y, Han SJ, Kim SK and Hong SM: The therapeutic effect of hyperbaric oxygen therapy in patients with severe to profound idiopathic sudden sensorineural hearing loss. Sci Rep. 14:33212024. View Article : Google Scholar : PubMed/NCBI | |
|
Zahorec R: Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 102:5–14. 2001.(In English, Slovak). PubMed/NCBI | |
|
Xi J, Liu H and Wang X: Prostaglandin E1 effects on CD62p and PAC-1 in patients with sudden sensorineural hearing loss. Thromb Res. 188:31–38. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Gupta M and Somasundaram I: Hyperbaric chambers: Design and function. Hyperbaric Oxygen Therapy: Principles and Applications. Springer Nature Singapore; Singapore: pp. 31–36. 2023, View Article : Google Scholar | |
|
Hu Y, Ye Y, Ji X and Wu J: The role of hyperbaric oxygen in idiopathic sudden sensorineural hearing loss. Med Gas Res. 14:180–185. 2024. View Article : Google Scholar : PubMed/NCBI | |
|
Mathieu D, Marroni A and Kot J: Tenth european consensus conference on hyperbaric medicine: Preliminary report. Diving Hyperb Med. 46:122–123. 2016.PubMed/NCBI | |
|
Kim H, Kong SK, Kim J, Lee HM, Choi SW, Lee IW and Oh SJ: The optimized protocol of hyperbaric oxygen therapy for sudden sensorineural hearing loss. Laryngoscope. 133:383–388. 2023. View Article : Google Scholar : PubMed/NCBI | |
|
Chen C, Hu H and Chen RY: Varied effects exerted on sudden sensorineural hearing loss through HBO2 therapeutic pressure. Undersea Hyperb Med Fourth Quarter. 48:417–423. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Umesawa M, Kobashi G, Kitoh R, Nishio SY, Ogawa K, Hato N, Sone M, Fukuda S, Hara A, Ikezono T, et al: Relationships among drinking and smoking habits, history of diseases, body mass index and idiopathic sudden sensorineural hearing loss in Japanese patients. Acta Otolaryngol. 137 (sup565):S17–S23. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Lam M, Bao Y, Hua GB and Sommer DD: Sudden sensorineural hearing loss and metabolic syndrome: A systematic review and meta-analysis. Otol Neurotol. 42:1308–1313. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Holy R, Navara M, Dosel P, Fundova P, Prazenica P and Hahn A: Hyperbaric oxygen therapy in idiopathic sudden sensorineural hearing loss (ISSNHL) in association with combined treatment. Undersea Hyperb Med. 38:137–142. 2011.PubMed/NCBI | |
|
Yıldırım E, Murat Özcan K, Palalı M, Cetin MA, Ensari S and Dere H: Prognostic effect of hyperbaric oxygen therapy starting time for sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol. 272:23–28. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Wang HH, Chen YT, Chou SF, Lee LC, Wang JH, Lai YH and Chang HT: Effect of the timing of hyperbaric oxygen therapy on the prognosis of patients with idiopathic sudden sensorineural hearing loss. Biomedicines. 11:26702023. View Article : Google Scholar : PubMed/NCBI | |
|
Choi Y, Choi HL, Jeong AY, Kang WS, Park HJ, Chung JW and Ahn JH: Hyperbaric oxygen (HBO) therapy as an effective approach to the treatment of patients with severe idiopathic sudden sensorineural hearing loss. Acta Otolaryngol. 140:383–386. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu Y, He S, Liao K, Li M, Zhao Z and Jiang H: Clinical profiles and prognoses of adult patients with full-frequency sudden sensorineural hearing loss in combination therapy. J Clin Med. 12:14782023. View Article : Google Scholar : PubMed/NCBI | |
|
Fu Q, Duan R, Sun Y and Li Q: Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics. Redox Biol. 53:1023522022. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Y, Zhou Y, Jia Y, Wang T and Meng D: Adverse effects of hyperbaric oxygen therapy: A systematic review and meta-analysis. Front Med (Lausanne). 10:11607742023. View Article : Google Scholar : PubMed/NCBI | |
|
Wilson WR, Byl FM and Laird N: The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol. 106:772–776. 1980. View Article : Google Scholar : PubMed/NCBI | |
|
Wei BP, Stathopoulos D and O'Leary S: Steroids for idiopathic sudden sensorineural hearing loss. Cochrane Database Syst Rev. 2013:CD0039982013.PubMed/NCBI | |
|
Akuter idiopathischer sensorineuraler hörverlust-steroidpulstherapie oder traditionelle orale prednisolon-therapie? Laryngorhinootologie. 95:748–749. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Huang J, Yang L, Cao X and Wang W: Differences in hearing recovery following intratympanic alone or intravenous dexamethasone with rescue intratympanic steroids for sudden sensorineural hearing loss: A randomised trial. Clin Otolaryngol. 46:546–551. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Skarżyńska MB, Kołodziejak A, Gos E, Sanfis MD and Skarżyński PH: Effectiveness of various treatments for sudden sensorineural hearing loss-a retrospective study. Life (Basel). 12:962022.PubMed/NCBI | |
|
Chin CS, Lee TY, Chen YW and Wu MF: Idiopathic sudden sensorineural hearing loss: Is hyperbaric oxygen treatment the sooner and longer, the better? J Pers Med. 12:16522022. View Article : Google Scholar : PubMed/NCBI | |
|
Si X, Yu Z, Ren X, Huang L and Feng Y: Efficacy and safety of standardized ginkgo biloba L. Leaves extract as an adjuvant therapy for sudden sensorineural hearing loss: A systematic review and meta-analysis. J Ethnopharmacol. 282:1145872022. View Article : Google Scholar : PubMed/NCBI | |
|
Agarwal L and Pothier DD: Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss. Cochrane Database Syst Rev. 2009:CD0034222009.PubMed/NCBI | |
|
Caragli V, Franz L, Incognito A, Bitonti S, Guarnaccia M, Cenedese R, Cocimano D, Romano A, Canova G, Zanatta P, et al: Prognostic factors in idiopathic sudden sensorineural hearing loss: The experience of two audiology tertiary referral centres. Medicina (Kaunas). 60:11302024. View Article : Google Scholar : PubMed/NCBI | |
|
Sanda N, Sawabe M, Kabaya K, Kawaguchi M, Fukushima A, Nakamura Y, Maseki S, Niwa M, Mori H, Hyodo Y, et al: Clinical impact of hyperbaric oxygen therapy combined with steroid treatment for sudden sensorineural hearing loss: A case-control study. Laryngoscope Investig Otolaryngol. 9:e12972024. View Article : Google Scholar : PubMed/NCBI | |
|
Lee JW, Kim H, Kong SK, Kim J, Choi SW and Oh SJ: The effectiveness of salvage hyperbaric oxygen therapy following combined steroid therapy for refractory sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol. 133:400–405. 2024. View Article : Google Scholar : PubMed/NCBI | |
|
Skarzynski PH, Kolodziejak A, Gos E, Skarzynska MB, Czajka N and Skarzynski H: Hyperbaric oxygen therapy as an adjunct to corticosteroid treatment in sudden sensorineural hearing loss: A retrospective study. Front Neurol. 14:12251352023. View Article : Google Scholar : PubMed/NCBI | |
|
Kayalı Dinç AS, Çayönü M, Boynueğri S, Ünsal Tuna E and Eryılmaz A: Is salvage hyperbaric oxygen therapy effective for sudden sensorineural hearing loss in patients with non-response to corticostreoid treatment? Cureus. 12:e65602020.PubMed/NCBI | |
|
Almosnino G, Holm JR, Schwartz SR and Zeitler DM: The role of hyperbaric oxygen as salvage therapy for sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol. 127:672–676. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Suzuki H, Kawaguchi R, Wakasugi T, Do BH, Kitamura T and Ohbuchi T: Efficacy of intratympanic steroid on idiopathic sudden sensorineural hearing loss: An analysis of cases with negative prognostic factors. Am J Audiol. 28:308–314. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Yang CH, Wu RW and Hwang CF: Comparison of intratympanic steroid injection, hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss. Otol Neurotol. 34:1411–1416. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Sun H, Qiu X, Hu J and Ma Z: Comparison of intratympanic dexamethasone therapy and hyperbaric oxygen therapy for the salvage treatment of refractory high-frequency sudden sensorineural hearing loss. Am J Otolaryngol. 39:531–535. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Cavaliere M, De Luca P, Scarpa A, Strzalkowski AM, Ralli M, Calvanese M, Savignano L, Viola P, Cassandro C, Chiarella G and Di Stadio A: Combination of hyperbaric oxygen therapy and oral steroids for the treatment of sudden sensorineural hearing loss: Early or late? Medicina (Kaunas). 58:14212022. View Article : Google Scholar : PubMed/NCBI | |
|
Oya R, Horii A, Akazawa H, Osaki Y and Inohara H: Prognostic predictors of sudden sensorineural hearing loss in defibrinogenation therapy. Acta Otolaryngol. 136:271–276. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Celik A and Akil F: Treatment effectiveness according to frequencies in patients with sudden sensorineural hearing loss. Cir Cir. 92:795–803. 2024.PubMed/NCBI | |
|
Mariani C, Carta F, Catani G, Lobina S, Marrosu V, Corrias S, Tatti M and Puxeddu R: Idiopathic sudden sensorineural hearing loss: effectiveness of salvage treatment with intratympanic dexamethasone or hyperbaric oxygen therapy in addition to systemic steroids. Front Neurol. 14:12252062023. View Article : Google Scholar : PubMed/NCBI | |
|
Včeva A, Zubčić Ž, Mihalj H, Maleš J, Mendeš T and Šestak A: Pretreatment hearing grades and hearing recovery outcomes after primary hyperbaric oxygen treatment in patients with idiopathic sudden sensorineural hearing loss. Diving Hyperb Med. 52:191–196. 2022. View Article : Google Scholar : PubMed/NCBI | |
|
Dova S, Psillas G, Tsaligopoulos M, Nikolaidis V, Stefanidou S, Karagiannis G, Kotsiou M, Kaltzidis T and Markou K: The effectiveness of hyperbaric oxygen therapy on the final outcome of patients with sudden sensorineural hearing loss. Am J Otolaryngol. 43:1035642022. View Article : Google Scholar : PubMed/NCBI | |
|
Huo Z, Cheng X, Gu J, Hong Y, Wang Z and Zhang Z: Prognostic factors for hearing outcomes in patients that undergo adjuvant hyperbaric oxygen therapy for sudden sensorineural hearing loss. Laryngoscope Investig Otolaryngol. 7:592–598. 2022. View Article : Google Scholar : PubMed/NCBI | |
|
Huang C, Tan G, Xiao J and Wang G: Efficacy of hyperbaric oxygen on idiopathic sudden sensorineural hearing loss and its correlation with treatment course: Prospective clinical research. Audiol Neurootol. 26:479–486. 2021. View Article : Google Scholar : PubMed/NCBI | |
|
Keseroğlu K, Toptaş G, Uluat A, Bayir Ö, Çadalli Tatar E, Saylam G, Korkmaz MH and Özdek A: Addition of intratympanic steroid or hyperbaric oxygen treatment to systemic steroid treatment in sudden idiopathic sensorineural hearing loss treatment, and long-term results of salvage treatment. Turk J Med Sci. 50:177–183. 2020.PubMed/NCBI | |
|
Cho I, Lee HM, Choi SW, Kong SK, Lee IW, Goh EK and Oh SJ: Comparison of two different treatment protocols using systemic and intratympanic steroids with and without hyperbaric oxygen therapy in patients with severe to profound idiopathic sudden sensorineural hearing loss: A randomized controlled trial. Audiol Neurootol. 23:199–207. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Hosokawa S, Hosokawa K, Takahashi G, Sugiyama KI, Nakanishi H, Takebayashi S and Mineta H: Hyperbaric oxygen therapy as concurrent treatment with systemic steroids for idiopathic sudden sensorineural hearing loss: A comparison of three different steroid treatments. Audiol Neurootol. 23:145–151. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Krajcovicova Z, Melus V, Zigo R, Matisáková I, Vecera J and Kaslíková K: Efficacy of hyperbaric oxygen therapy as a supplementary therapy of sudden sensorineural hearing loss in the Slovak republic. Undersea Hyperb Med. 45:363–370. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Khater A, El-Anwar MW, Nofal AA and Elbahrawy AT: Sudden sensorineural hearing loss: Comparative study of different treatment modalities. Int Arch Otorhinolaryngol. 22:245–249. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Chi TH, Chiang MC, Chen RF and Yuan CH: Does the addition of hyperbaric oxygen therapy to conventional treatment modalities influence the outcome of soldiers with idiopathic sudden sensorineural hearing loss? J R Army Med Corps. 164:69–71. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Ajduk J, Ries M, Trotic R, Marinac I, Vlatka K and Bedekovic V: Hyperbaric oxygen therapy as salvage therapy for sudden sensorineural hearing loss. J Int Adv Otol. 13:61–64. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Hosokawa S, Sugiyama KI, Takahashi G, Hashimoto YI, Hosokawa K, Takebayashi S and Mineta H: Hyperbaric oxygen therapy as adjuvant treatment for idiopathic sudden sensorineural hearing loss after failure of systemic steroids. Audiol Neurootol. 22:9–14. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Gülüstan F, Yazıcı ZM, Alakhras WME, Erdur O, Acipayam H, Kufeciler L and Kayhan FT: Intratympanic steroid injection and hyperbaric oxygen therapy for the treatment of refractory sudden hearing loss. Braz J Otorhinolaryngol. 84:28–33. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Ersoy Callioglu E, Tuzuner A, Demirci S, Cengiz C and Caylan R: Comparison of simultaneous systemic steroid and hyperbaric oxygen treatment versus only steroid in idiopathic sudden sensorineural hearing loss. Int J Clin Exp Med. 8:9876–9882. 2015.PubMed/NCBI | |
|
Capuano L, Cavaliere M, Parente G, Damiano A, Pezzuti G, Lopardo D and Iemma M: Hyperbaric oxygen for idiopathic sudden hearing loss: Is the routine application helpful? Acta Otolaryngol. 135:692–697. 2015. View Article : Google Scholar : PubMed/NCBI |
