Journal Articles

Article Open Access

Novel tetravalent bispecific antibody, PSMA/TRAIL‑R2 REGULGENT™, induces selective tumor cell apoptosis without hepatotoxicity

Makoto Nakayama, Sayaka Takagi‑Maeda, Yusuke Machino, Kaito Nihira, Miho Inoue, Nobuaki Takahashi, Katsuaki Usami

Article Number: 155 Published online on: 15 September 2025
Article Open Access

Senescence‑associated IL‑33 secretion undermines sorafenib efficacy in hepatocellular carcinoma via immune evasion

Yu-Xin Lin, Hsien Liu, Wei-Chiao Liao, Yi-Ching Wang, Bo-Cheng Zhang, Shu-Wen Wan, Chien-Chin Chen, Chih-Peng Chang

Article Number: 154 Published online on: 15 September 2025
Review Open Access

Ursolic acid: A natural pentacyclic triterpenoid with clinical promise in gynecological and breast cancers (Review)

Tingting Chen, Shirun Sun, Zhengli Zhou, Xiuqin Zhang

Article Number: 153 Published online on: 11 September 2025
Review Open Access

ISG20: The multifaceted ‘molecular star’ in cancer research (Review)

Xinhui Zhu, Shihao Jiang, Lipeng Zhang, Shaojian Zou, Houqin Zhang, Jingyu Zhang, Liyu Chen, Hui Li, Zhen Zong

Article Number: 152 Published online on: 11 September 2025
Article Open Access

Irradiation‑induced cellular senescence is linked to pro‑survival signaling and checkpoint regulation in a 2D and 3D model for head and neck cancer

Luis Bugia, Annette Affolter, Johann Kern, Emma Sohn, Frederic Jungbauer, Jens Fleckenstein, Anne Lammert, Nicole Rotter, Claudia Scherl

Article Number: 151 Published online on: 09 September 2025
Expression of Concern Open Access

[Expression of Concern] miR‑30a inhibits glioma progression and stem cell‑like properties by repression of Wnt5a

Yonghong Zhang, Zhi Wu, Lichao Li, Min Xie

Article Number: 150 Published online on: 04 September 2025
Article Open Access

DBN1‑mediated upregulation of GAB2 facilitates the migration and invasion of T‑cell acute lymphoblastic leukemia cells

Jiaxing Sun, Xiaoxing Huang, Xingruo Zeng, Yufei Lei, Hengjing He, Zimeng Wei, Di Xiao, Qiuping Zhang, Xinran Li, Fuling Zhou, Liang Shao

Article Number: 149 Published online on: 03 September 2025
Review Open Access

Lactylation modification in lung cancer: A review of current research and future directions (Review)

Qingguo Lv, Jianan Xu, Na Hu, Yujun Zhao, Xin Wang, Tan Wang, Lin Tian

Article Number: 148 Published online on: 01 September 2025
Article Open Access

BUB1B promotes homologous recombination‑mediated DNA damage repair in breast cancer cells through the PI3K/AKT signaling pathway

Xuewen Luo, Yuqin Wei, Hanxin Lin, Ning Xiao, Wei Zhao

Article Number: 147 Published online on: 01 September 2025
Article Open Access

Serum from patients with oral squamous cell carcinoma remodels the tumor immune escape ecological niche by promoting regulatory T‑cell differentiation and T‑cell exhaustion

Hongli Chen, Jiao Chen, Bomiao Cui, Die Lv, Wenwen Han, Yun Feng, Ping Zhang

Article Number: 145 Published online on: 26 August 2025
Article Open Access

T cell exhaustion‑related gene CD79B predicts prognosis, inhibits malignant progression and promotes tumor‑associated macrophage M1‑like polarization in lung adenocarcinoma

Xia Wu, Chunhui Qu, Yiting Ouyang, Lifang Yang, Wuzhong Jiang

Article Number: 144 Published online on: 25 August 2025
Correction Open Access

[Corrigendum] Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer

Xiaoning Yuan, Te Zhang, Xin Zheng, Yunfei Zhang, Tingting Feng, Pengfei Liu, Zhiting Sun, Shanshan Qin, Xuewen Liu, Liang Zhang, Jie Song, Ying Liu

Article Number: 143 Published online on: 21 August 2025
Review Open Access

Role of autophagy‑modulating long non‑coding RNAs in tumor radioresistance (Review)

Hailong Li, Zhengxi He

Article Number: 142 Published online on: 21 August 2025
Review Open Access

Emerging dual role of ferroptosis in lung cancer (Review)

Anqi Wu, Yingchen Ni, Youlang Zhou, Jiahai Shi

Article Number: 141 Published online on: 21 August 2025
Retraction Open Access

[Retracted] Tumor‑released lncRNA H19 promotes gefitinib resistance via packaging into exosomes in non‑small cell lung cancer

Yi Lei, Wang Guo, Bowang Chen, Lu Chen, Jiaxin Gong, Weimin Li

Article Number: 140 Published online on: 12 August 2025
Review

Circular RNAs in colorectal cancer: From molecular mechanisms to therapeutic applications (Review)

Yuxing He, Can Luo, Wei Du, Debei Liu, Lingshan Liao, Siqian Wang, Yanlin Cao

Article Number: 139 Published online on: 11 August 2025
Expression of Concern Open Access

[Expression of Concern] Lysine demethylase 2A promotes the progression of ovarian cancer by regulating the PI3K pathway and reversing epithelial‑mesenchymal transition

Dan-Hua Lu, Jiang Yang, Li-Kun Gao, Jie Min, Jian-Ming Tang, Ming Hu, Yang Li, Su-Ting Li, Jing Chen, Li Hong

Article Number: 138 Published online on: 08 August 2025
Review Open Access

Lymphadenectomy in upper tract urothelial carcinoma: Clinical insights and controversies (Review)

Dihao Lv, Yinglong Huang, Haihao Li, Shi Fu, Chen Gong, Chadanfeng Yang, Jiansong Wang, Haifeng Wang, Zhiyong Tan, Mingxia Ding

Article Number: 137 Published online on: 08 August 2025
Review Open Access

Role of osteopontin in cancer: From pathogenesis to therapeutics (Review)

Wenli Xu, Zhifei Bi, Li Lu, Fuqiang Feng, Laizhao Chen, Chengwu Zhang

Article Number: 136 Published online on: 07 August 2025
Correction Open Access

[Corrigendum] Identification of TYMS as a promoting factor of retroperitoneal liposarcoma progression: Bioinformatics analysis and biological evidence

Sha Zhang, Liang Yan, Can Cui, Zhen Wang, Jianhui Wu, Min Zhao, Bin Dong, Xiaoya Guan, Xiuyun Tian, Chunyi Hao

Article Number: 135 Published online on: 06 August 2025
Journal Cover

November-2025
Volume 54 Issue 5

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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