Open Access

Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review)

  • Authors:
    • Sharanya Manoharan
    • Oviya Ramalakshmi Iyappan
    • Archana Prabahar
    • Balu Bhasuran
    • Kalpana Raja
  • View Affiliations

  • Published online on: July 15, 2025     https://doi.org/10.3892/wasj.2025.376
  • Article Number: 88
  • Copyright : © Manoharan et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

The association of human respiratory diseases and the gut microbiota is a novel diagnostic area for the exploration of health research. The gut microflora is a naturally occurring symbiotic environment that is greatly required for various biological processes. It has been also now found that the alterations in the organisms is directly linked with the extent of invasion by disease. The present review article discusses the microbiome of the gut‑lung axis in different respiratory disorders, associated beneficial microbes in reverting the disorders, and nutrient supplementation in the form of prebiotics and probiotics in order to incorporate the healthy gut microbiota. The present review also discusses the technologies including the concepts of omics, text mining and machine learning approaches in the field of precision medicine research.
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September-October 2025
Volume 7 Issue 5

Print ISSN: 2632-2900
Online ISSN:2632-2919

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Copy and paste a formatted citation
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Spandidos Publications style
Manoharan S, Iyappan OR, Prabahar A, Bhasuran B and Raja K: Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review). World Acad Sci J 7: 88, 2025.
APA
Manoharan, S., Iyappan, O.R., Prabahar, A., Bhasuran, B., & Raja, K. (2025). Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review). World Academy of Sciences Journal, 7, 88. https://doi.org/10.3892/wasj.2025.376
MLA
Manoharan, S., Iyappan, O. R., Prabahar, A., Bhasuran, B., Raja, K."Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review)". World Academy of Sciences Journal 7.5 (2025): 88.
Chicago
Manoharan, S., Iyappan, O. R., Prabahar, A., Bhasuran, B., Raja, K."Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review)". World Academy of Sciences Journal 7, no. 5 (2025): 88. https://doi.org/10.3892/wasj.2025.376