An enchondroma is a benign cartilaginous tumor of the bone. The present study describes a case of a symptomatic enchondroma in the proximal phalanx of the left second toe. A 20‑year‑old male patient presented with a painless, progressively enlarging mass on the left second toe, which had resulted in gradual deformity over the past 6 months. Over the past 2 weeks, the lump has caused him pain while wearing shoes, hindering his daily activities. An X‑ray revealed a radiolucent, eccentric lesion with loss of the medial bone cortex. Magnetic resonance imaging revealed an expansile osteolytic lesion breaching three cortices with no soft tissue involvement, consistent with an enchondroma. The surgical removal of the lesion and autologous iliac bone grafting were performed, and the histopathological analysis of the tumor revealed hypercellular sheets of chondrocytes encased by mature bone trabeculae without cortical destruction, pre‑existing lamellar bone entrapment, or soft tissue invasion. Following a 6‑month follow‑up period, the patient was in a good condition, without any recurrence or complications. In addition, the present study performed a review of 19 cases of enchondroma in different foot locations. The management of these cases included excision with bone grafting, curettage with or without grafting, total phalangectomy and amputation. There were no cases of recurrence. On the whole, in symptomatic patients with enchondroma, the surgical removal of the lesion and autologous iliac bone grafting may result in a good outcome.

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