Most Read
Discover the most frequently read articles from the past month
Article

Histone modifications in cervical cancer: Epigenetic mechanisms, functions and clinical implications (Review)
Xuewei Li, Min Zhou, Jing Yu, Shaohui Yu, Zheng Ruan
Article Number: 131 Published online on: 01 August 2025
Review

Liver metastasis of colorectal cancer: Mechanism and clinical therapy (Review)
Changjiang Yang, Long Zhao, Caihong Wang, Yingjiang Ye, Zhanlong Shen
Article Number: 130 Published online on: 01 August 2025
Article
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function
Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Pages: 1465-1474 Published online on: 13 January 2015
Review

ARID1A gene mutation in ovarian and endometrial cancers (Review)
Takashi Takeda, Kouji Banno, Ryuichiro Okawa, Megumi Yanokura, Moito Iijima, Haruko Irie‑Kunitomi, Kanako Nakamura, Miho Iida, Masataka Adachi, Kiyoko Umene, Yuya Nogami, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
Pages: 607-613 Published online on: 16 November 2015
Review
The emerging landscape of circular RNA ciRS-7 in cancer (Review)
Li Peng, Xiao Qing Yuan, Guan Cheng Li
Pages: 2669-2674 Published online on: 08 April 2015
Article

Comprehensive genetic profiling using tissue and blood in locally advanced tumors
Kenji Fujiyoshi, Rie Sugihara, Naoki Miyamoto, Yoriko Watanabe, Tomoya Sudo, Sanae Numata, Jun Akiba, Hideyuki Abe, Yuka Ichinose, Kenji Inoue, Shuichi Ozono, Takeharu Ono, Kentaro Orioka, Masaki Kashihara, Ryousuke Kajiwara, Hiroyuki Kawano, Akihiko Kawahara, Ryuta Takase, Uhi Toh, Kazuaki Hashimoto, Toru Hisaka, Shingo Hirai, Masahiro Mitsuoka, Daiki Miyazaki, Fumi Yoshitomi, Ken Yamamoto, Hirohito Umeno, Masahisa Nomura, Yoshiki Naito
Article Number: 134 Published online on: 05 August 2025
Review

O‑GlcNAcylation as an emerging molecular target for cholangiocarcinoma therapy (Review)
Purin Charoensuksai, Siwanon Jirawatnotai
Article Number: 119 Published online on: 18 July 2025
Review

Changing landscape of advanced esophageal squamous cell carcinoma: Breakthroughs in systemic therapies (Review)
Yueyue Li, Jingjing Li, Wenhui Mo, Xuanfu Xu
Article Number: 120 Published online on: 18 July 2025
Review
Long noncoding RNAs in digestive system cancers: Functional roles, molecular mechanisms, and clinical implications (Review)
Min Fu, Chen Zou, Lei Pan, Wei Liang, Hui Qian, Wenrong Xu, Pengcheng Jiang, Xu Zhang
Pages: 1207-1218 Published online on: 11 July 2016
Review

Advances in the chemo‑preventive effects and mechanisms of ursolic acid against lung cancer (Review)
Zhanyu Lin, Qingze Chen, Zhaoyue Chen, Tianyang Peng, Jinglu Bai, Fengjun Ma
Article Number: 126 Published online on: 25 July 2025
Review

Potential therapeutic target in oncology: Protein palmitoylation (Review)
Shiping Hao, Yongming Mei, Shaolin Chen, Jing Liu, Yao Zhang, Zhengfeng Zhu, Kangjia Zuo
Article Number: 117 Published online on: 16 July 2025
Review
CAR T cell therapy: A new era for cancer treatment (Review)
Rimjhim Mohanty, Chitran Roy Chowdhury, Solomon Arega, Prakriti Sen, Pooja Ganguly, Niladri Ganguly
Pages: 2183-2195 Published online on: 24 September 2019
Article

Loperamide reverses 5‑FU resistance in colorectal cancer by activating autophagy
Juan Yu, Xiaotong An, Xinyang Qu, Jing Ke, Huiling Rao, Yang Liu, Zhixin Liu, Danwen Liu, Jie Jia, Shan Li
Article Number: 133 Published online on: 04 August 2025
Article

PTP4A1 promotes intrahepatic cholangiocarcinoma development and progression by interacting with PTEN and activating the PI3K/AKT/GSKα axis
Ou Li, Yuhuai Peng, Jinhui Che, Yubin Liu
Article Number: 125 Published online on: 25 July 2025
Review
Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (Review)
Rubí Viedma-Rodríguez, Luis Baiza-Gutman, Fabio Salamanca‑Gómez, Mariana Diaz‑Zaragoza, Guadalupe Martínez-Hernández, Ruth Ruiz Esparza‑Garrido, Miguel Angel Velázquez-Flores, Diego Arenas-Aranda
Pages: 3-15 Published online on: 16 May 2014
Article

Visfatin facilitates esophageal cancer migration by suppressing miR‑3613‑5p expression and promoting VEZF1/VCAN production
Chang-Lun Huang, Shubham Suresh Ghule, Yu-Hsiang Chang, Hsiao-Chi Tsai, Ming-Yu Lien, Jeng-Hung Guo, Chun-Lin Liu, Po-I Liu, Chih-Hsin Tang
Article Number: 128 Published online on: 29 July 2025
Article

Genome‑wide investigation of the clinical significance and prospective molecular mechanisms of kinesin family member genes in patients with lung adenocarcinoma
Linbo Zhang, Guangzhi Zhu, Xiangkun Wang, Xiwen Liao, Rui Huang, Chunxia Huang, Ping Huang, Jianquan Zhang, Peng Wang
Pages: 1017-1034 Published online on: 16 July 2019
Article
β-elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter
Hui-Qin Guo, Guan-Nan Zhang, Yi-Jun Wang, Yun-Kai Zhang, Kamlesh Sodani, Tanaji T. Talele, Charles R. Ashby, Zhe-Sheng Chen
Pages: 858-866 Published online on: 27 November 2013
Article
miR-186, miR-3651 and miR-494: Potential biomarkers for oral squamous cell carcinoma extracted from whole blood
Jutta Ries, Eleftherios Vairaktaris, Abbas Agaimy, Rita Kintopp, Christoph Baran, Friedrich W. Neukam, Emeka Nkenke
Pages: 1429-1436 Published online on: 20 January 2014
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